REDEFINING THE
FUTURE OF CAR T

Arie Belldegrun, M.D., is the Executive Chairman and Co-Founder of Allogene. He currently serves as Chairman of Two River Group, UroGen Pharma, Kronos Bio, and as Co-Chairman of Breakthrough Properties. He is also on the Board of Gingko Bioworks, IconOVir, ByHeart, and is a Co-Founder and Senior Managing Director of Vida Ventures. As a visionary entrepreneur, Arie has had a distinguished tenure in the life sciences, having been closely involved with the founding and advancement of several successful biopharmaceutical companies including Cougar Biotechnology and Agensys. ZYTIGA® (abiraterone acetate), developed by Cougar, is a mainstay of therapy for patients with metastatic prostate cancer. Arie also founded Kite Pharma, a recognized leader in CAR T therapy where he served as Chairman, President and Chief Executive Officer until the acquisition of Kite by Gilead Sciences in October 2017. Arie is a Research Professor, holds the Roy and Carol Doumani Chair in Urologic Oncology, and is Director of the Institute of Urologic Oncology at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Prior to joining UCLA, Arie was at the National Cancer Institute/ National Institutes of Health as a research fellow in surgical oncology and immunotherapy under Dr. Steven A. Rosenberg. He has authored several books on oncology and more than 500 scientific and medical papers related to urological cancers, immunotherapy, gene therapy and cancer vaccines. He is also certified by the American Board of Urology and is a member of the American Association of Genitourinary Surgeons. He completed his M.D. at the Hebrew University Hadassah Medical School in Jerusalem, his post-graduate studies in immunology at the Weizmann Institute of Science, and his residency in urologic surgery at Harvard Medical School.

Zachary Roberts, M.D., Ph.D., is the President and Chief Executive Officer of Allogene Therapeutics. A trained immunologist, board-certified oncologist, and veteran of cell therapy development, Zachary brings extensive experience in clinical oncology, translational research, and the advancement of innovative cell therapies. He previously served as Allogene’s Executive Vice President of Research & Development and Chief Medical Officer. Before joining Allogene, Zachary was Chief Medical Officer of Instil Bio, where he led development of both clinical and pre-clinical programs. Prior to that, he held various roles of increasing responsibility at Kite Pharma (acquired by Gilead in 2017), where he was instrumental in the development and execution of the ZUMA trials across multiple indications for YESCARTA®, the first autologous CAR T therapy approved for non-Hodgkin lymphoma. Before joining Kite, Zachary led several solid tumor studies at Amgen. He holds an M.D. and Ph.D. in immunology from the University of Maryland, Baltimore and completed clinical and post-graduate training at Massachusetts General Hospital and the Dana-Farber Cancer Institute.

Ben Beneski is the Senior Vice President and Chief Technical Officer of Allogene. With a career spanning more than two decades in biologics manufacturing and technical operations, Ben brings a wealth of experience and strategic vision to Allogene. He joined Allogene in 2019 as Executive Director and Plant Manager, where he played a pivotal role in the design, construction, and successful startup of Cell Forge 1, the company’s cutting-edge manufacturing facility. During his time at Allogene, Ben has advanced through a series of increasingly senior roles, including Vice President of Manufacturing and Vice President of Product Development and Manufacturing where he led the development of next-generation platforms, effectively managed internal and external manufacturing networks, and drove key initiatives to support IND submissions and ensure commercial readiness. Prior to joining Allogene, Ben held senior manufacturing roles at various biotechnology companies, including Vir Biotechnology and Amgen. He holds a Master’s in Business Administration from Northeastern University and a Bachelor’s Degree in Chemical Engineering from Stevens Institute of Technology.

Christine Cassiano is the Executive Vice President, Chief Corporate Affairs and Brand Strategy Officer and one of the founders of Allogene. Christine is a communications executive with wide experience in investor relations, corporate communications, media relations, brand strategy and public affairs. Christine’s career is distinguished by the development of integrated communications strategies for companies with novel therapies such as YESCARTA® (axicabtagene ciloleucel) and BOTOX®/BOTOX® Cosmetic (onabotulinumtoxinA). Prior to Allogene, Christine served as Senior Vice President of Corporate Communications and Investor Relations for Kite until its acquisition by Gilead Sciences in 2017. Prior to that, she was the Head of Healthcare for W2O Group (now Real Chemistry). In 2012, Christine co-founded ARC2 Communications & Media, a boutique agency that developed groundbreaking platforms for some of the largest companies in healthcare. Before, she served as Senior Vice President and Co-Director, Healthcare, at Hill + Knowlton Strategies. Christine also held senior global communications roles in biotechnology and pharmaceutical companies, including Amgen, which also included an expatriate assignment in Switzerland overseeing all European communications, Allergan and Abraxis BioScience. Some of Christine’s career achievements include a SABRE Silver Anvil Award for the launch of BOTOX® Cosmetic (Allergan), an In2 SABRE Award for the Most Innovative Brand/Agency Collaboration (Pfizer/ARC2), and PR Week’s 40 Under 40. Christine serves as a Senior Strategic Advisor to Urogen Pharma and Vida Ventures. She holds an M.A. in Psychology from Pepperdine University, a B.A. in Communications from California State University, Fullerton, and an Investor Relations Certification (IRC) from the University of California, Irvine.

Earl Douglas is the General Counsel and Compliance Officer of Allogene. Earl has 40 years of experience as an attorney, serving as legal counsel for publicly traded biotech and medical device companies as well as start-ups. In these roles, Earl advised management and boards on a wide range of legal and strategic matters, including corporate governance, SEC filings, commercial transactions, intellectual property strategy, mergers and acquisitions, corporate finance, litigation, and compliance programs. Most recently, Earl served as General Counsel of Applied Molecular Transport. Prior to that role, he served in the same capacity for Kiverdi. He has also served as General Counsel and Corporate Secretary at BioMimetic Therapeutics (acquired by Wright Medical Group), Spinal Dynamics (acquired by Medtronic), and OPX Biotechnologies (acquired by Cargill). He previously served as Counsel with Wilson Sonsini Goodrich & Rosati, and earlier in his career practiced as an Associate with Weil, Gotshal & Manges. In addition, Earl currently serves as a member of the board of directors of Lynch Regenerative Medicine, LLC. Earl holds a J.D. from Columbia University School of Law and a B.S. in Chemical Engineering from the Massachusetts Institute of Technology (MIT).

Susie Lundeen is the Chief People Officer of Allogene. Susie has held leadership roles in the full life cycle of global human resources, talent acquisition, operations, mergers and acquisitions, and business expansion at several biotechnology companies. She was most recently with Unity Biotechnology where she served as Chief Human Resources Officer for six years. Prior to Unity, Susie was Senior Vice President of Human Resources at Kythera Biopharmaceuticals where she was responsible for designing and implementing all people systems supporting the company, from early product development to drug approval and eventual commercial launch until its acquisition by Allergan. From 2005 to 2007, Susie was Vice President of Human Resources and Administration at Activus Healthcare Solutions, Inc., a healthcare company that was acquired by PSS, Inc. Prior to that experience, she held various positions at Amgen, including an expatriate assignment to support the build-out of Amgen’s world-wide distribution facility in the Netherlands. She also served as Strategic HR Business Partner for Research & Development, and ultimately served as Senior Director of Human Resources responsible for Strategic Staffing and Succession Planning. Susie received a B.A. in psychology and business administration from California Lutheran University and is a trustee on the university’s Board of Regents.

Geoffrey (Geoff) Parker is the Executive Vice President, Chief Financial Officer of Allogene. He is a seasoned biotech and banking executive with nearly 40 years of leadership experience managing world-class finance and business development organizations. Geoff has directed and managed a broad range of strategic business and finance initiatives, including equity and debt financing, initial public offerings, and business development transactions. Prior to joining Allogene, Geoff served as Chief Operating Officer, Chief Financial Officer and Executive Vice President of Tricida, Inc., which focused on the development of an investigational drug candidate for metabolic acidosis in patients with chronic kidney disease. Prior to that, he served as Chief Financial Officer of Anacor Pharmaceuticals, which was acquired by Pfizer in 2016 for approximately $5.2 billion, and served as a Managing Director at Goldman Sachs, where he led the West Coast Healthcare Investment Banking group. In addition, Geoff currently serves as a member of the board of directors of Better Therapeutics and of Perrigo Company plc. He earned a B.A. with a double major in Economics and Engineering Sciences from Dartmouth College and an MBA from the Stanford Graduate School of Business.

Annie Yoshiyama is the Senior Vice President, Finance and Corporate Controller, and Principal Accounting Officer of Allogene. She is a seasoned finance and accounting executive with 20 years of experience spanning financial planning and analysis, corporate accounting, financial reporting, technical accounting, and equity and debt financing transactions. At Allogene, Annie has led equity financing initiatives in addition to her core accounting and reporting responsibilities. Prior to joining Allogene in 2024, Annie served as Vice President, Finance and Controller at AN2 Therapeutics, Inc. Before that, she spent nearly five years at Tricida, Inc., advancing from Associate Director to Senior Vice President, Finance and Chief Accounting Officer. Earlier in her career, Annie spent a decade at Dolby Laboratories in roles of increasing seniority within financial reporting and technical accounting and financial planning and analysis, and began her career in audit at PricewaterhouseCoopers LLP. She earned her Bachelor of Science and Master of Accounting degrees from the University of Southern California and is a licensed certified public accountant.

Arie Belldegrun, M.D., is the Executive Chairman and Co-Founder of Allogene. He currently serves as Chairman of Two River Group, UroGen Pharma, Kronos Bio, and as Co-Chairman of Breakthrough Properties. He is also on the Board of Gingko Bioworks, IconOVir, ByHeart, and is a Co-Founder and Senior Managing Director of Vida Ventures. As a visionary entrepreneur, Arie has had a distinguished tenure in the life sciences, having been closely involved with the founding and advancement of several successful biopharmaceutical companies including Cougar Biotechnology and Agensys. ZYTIGA® (abiraterone acetate), developed by Cougar, is a mainstay of therapy for patients with metastatic prostate cancer. Arie also founded Kite Pharma, a recognized leader in CAR T therapy where he served as Chairman, President and Chief Executive Officer until the acquisition of Kite by Gilead Sciences in October 2017. Arie is a Research Professor, holds the Roy and Carol Doumani Chair in Urologic Oncology, and is Director of the Institute of Urologic Oncology at the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Prior to joining UCLA, Arie was at the National Cancer Institute/ National Institutes of Health as a research fellow in surgical oncology and immunotherapy under Dr. Steven A. Rosenberg. He has authored several books on oncology and more than 500 scientific and medical papers related to urological cancers, immunotherapy, gene therapy and cancer vaccines. He is also certified by the American Board of Urology and is a member of the American Association of Genitourinary Surgeons. He completed his M.D. at the Hebrew University Hadassah Medical School in Jerusalem, his post-graduate studies in immunology at the Weizmann Institute of Science, and his residency in urologic surgery at Harvard Medical School.

Zachary Roberts, M.D., Ph.D., is the President and Chief Executive Officer of Allogene Therapeutics. A trained immunologist, board-certified oncologist, and veteran of cell therapy development, Zachary brings extensive experience in clinical oncology, translational research, and the advancement of innovative cell therapies. He previously served as Allogene’s Executive Vice President of Research & Development and Chief Medical Officer. Before joining Allogene, Zachary was Chief Medical Officer of Instil Bio, where he led development of both clinical and pre-clinical programs. Prior to that, he held various roles of increasing responsibility at Kite Pharma (acquired by Gilead in 2017), where he was instrumental in the development and execution of the ZUMA trials across multiple indications for YESCARTA®, the first autologous CAR T therapy approved for non-Hodgkin lymphoma. Before joining Kite, Zachary led several solid tumor studies at Amgen. He holds an M.D. and Ph.D. in immunology from the University of Maryland, Baltimore and completed clinical and post-graduate training at Massachusetts General Hospital and the Dana-Farber Cancer Institute.

David Chang, M.D., Ph.D., is the Co-Founder and former President and Chief Executive Officer of Allogene Therapeutics where he continues to serve on the Board of Directors. Previously, David was the Executive Vice President, Research & Development and Chief Medical Officer of Kite, a Gilead Company. He has an industry-leading track record of advancing breakthrough immunotherapies, having led the development of Yescarta® (the first CAR T therapy approved for non-Hodgkin lymphoma), Blincyto® (a first-in-class bispecific T cell engager antibody for acute lymphocytic leukemia), and IMLYGIC® (a first-of-its-kind oncolytic immunotherapy for melanoma). From 2002 to 2014, he held senior leadership roles at Amgen. Prior to entering the biotechnology industry, Dr. Chang held a faculty appointment in Medicine and Microbiology, Immunology & Molecular Genetics at the UCLA David Geffen School of Medicine. He earned his B.S. in biology from the MIT and an M.D. and Ph.D. from Stanford University, and completed a postdoctoral fellowship at MIT alongside postgraduate clinical training at Brigham and Women’s Hospital and Dana-Farber Cancer Institute.

Liz Barrett is the President and CEO of UroGen Pharma, a biotechnology company that develops and commercializes treatments for urologic and uro-oncological conditions. At UroGen, Liz spearheaded the 2020 approval of Jelmyto® for the treatment of low-grade upper tract urothelial carcinoma. She previously served as CEO of Novartis Oncology, where she managed the development and launch of the autologous CAR T therapy Kymriah® (tisagenlecleucel). Prior to her tenure at Novartis, she held several leadership positions at Pfizer, including Global President and General Manager of Oncology, and led the rollout of Ibrance®. She has also held leadership roles at Cephalon and Johnson & Johnson. Ms. Barrett currently serves on the Board of Directors of Sage Therapeutics.

John DeYoung is Vice President of Worldwide Business Development for Pfizer Oncology. He is a member of the Oncology Leadership Team and the Worldwide Business Development Leadership Team. John joined Pfizer in 1991 and has held leadership positions in Finance, Marketing, Commercial Development and Business Development. He received a bachelor’s degree in business from Michigan State University and an M.B.A. from the University of Chicago.

Franz Humer is Lead Independent Director of Allogene, Chairman of Neogene Therapeutics, and HMNC Brain Health. He is a Board Director of Cydar and Emil Frey Holdings and an Advisor to Temasek Holdings, Letterone Healthcare and Breakthrough Properties. In 1995, he joined Hoffmann-La Roche as a member of its Board and the head of its Pharmaceutical Division, progressing to become Chairman and CEO in 2001, and between 2008 and 2014 the Chairman of Roche Holding Limited. Franz joined the Board of Diageo in 2005, became Chairman in 2008 and retired in 2016. Before joining the Roche Group, he was the managing director of Glaxo Pharmaceuticals UK and Member of the Board of Glaxo Holdings plc. He progressed to be responsible for Research, Business Development, Manufacturing, Commercial Strategy, and all non-U.S. Operations for 13 years. Before that, he held various general management positions in Latin America and Europe for Schering-Plough Corporation. He is Chairman of the Board of Directors of the International Centre for Missing & Exploited Children and Chairman of the Humer Foundation. Franz earned a Ph.D. in law from the University of Innsbruck, Austria and an MBA from INSEAD in Fontainebleau, France.

Joshua is a Co-Founder and Director of Allogene Therapeutics. Joshua Kazam is a Co-Founder and Partner of Two River, where he has served as Partner since its inception in 2004. He is a Co-Founder and Partner of Vida Ventures, LLC, a life science investment firm, and was a Co-Founder and Director of Kite Pharma, where he served on the Board of Directors from inception until its acquisition by Gilead Sciences in 2017. Joshua also serves as a Director of several privately held companies including Kronos Bio, Hubble Contacts, ByHeart Inc, and Breakthrough Properties, LLC. Joshua is a Member of the Wharton School’s Undergraduate Executive Board and serves on the Board of the Desert Flower Foundation. He received his B.S. in Economics from the Wharton School of the University of Pennsylvania.

Stephen (Steve) Mayo is the Bren Professor of Biology and Chemistry and Merkin Institute Professor at the California Institute of Technology (Caltech) in Pasadena, California. He served as Vice Provost for Research at Caltech from 2007 to 2010 and Chair of its Division of Biology and Biological Engineering from 2010 to 2020. Dr. Mayo also serves on the Board of Directors of Merck & Co and Sarepta Therapeutics, Inc. He co-founded Molecular Simulations, Inc. (currently Accelrys/Biovia), a computational chemistry company; Xencor, Inc., a publicly traded bio-therapeutics company focused on developing next generation biologics for treating cancer; and Protabit, LLC, a privately held protein engineering company focused on the use of artificial intelligence and machine learning for protein engineering applications. In addition, he serves on the scientific advisory boards of Vida Ventures, Rubryc Therapeutics and Evozyne. Dr. Mayo was elected to the National Academy of Sciences in 2004 for his pioneering contributions in the field of protein design. He served as an elected board member for the American Association for the Advancement of Science from 2010 to 2014 and as a presidential appointee on the National Science Foundation’s National Science Board from 2013 to 2018. Dr. Mayo holds a B.S. in Chemistry from Pennsylvania State University and a Ph.D. in Chemistry from Caltech, and he completed postdoctoral work at both UC Berkeley and Stanford University School of Medicine in chemistry and biochemistry, respectively.

Debbie Messemer has more than 30 years of experience providing financial expertise to public and private companies and was the Managing Partner of KPMG’s Bay Area and Northwest region until her recent retirement. Debbie, a certified public accountant (CPA), joined KPMG LLP, the U.S. member firm of KPMG International, in 1982 and was admitted into partnership in 1995. As Managing Partner for the Bay Area and Northwest region, she was responsible for leading over 3,000 team members in 10 offices across all functions, including audit, tax and advisory. Debbie spent the majority of her career in KPMG’s audit practice as an audit engagement partner serving public and private clients in a variety of industry sectors. In addition to audit signing responsibilities, she has significant experience in SEC filings, due diligence, initial public offerings, mergers and acquisitions, and internal controls over financial reporting. Debbie is a member of the National Association of Corporate Directors (NACD) and of the San Francisco Chapter of Women Corporate Directors (WCD). She has served extensively on non-profit and advisory boards including the Bay Area Council, the San Francisco Committee on Jobs, the California Chamber of Commerce, the San Francisco Chamber of Commerce, the UC Berkeley Fisher Center Policy Advisory Board, San Francisco Ballet, and Posse. Debbie received a bachelor’s degree in accounting from the University of Texas at Arlington.

Vicki Sato served as President of Vertex Pharmaceuticals where she was responsible for research and development, business and corporate management, and commercial, legal and financial operations. Before joining Vertex, Dr. Sato was Vice President of Research at Biogen, Inc., where she led programs in inflammation, thrombosis, and HIV and contributed to the executive management of the company. She also served as a member of the Biogen Scientific Advisory Board. Dr. Sato began her career as a Professor in the Department of Cell and Developmental Biology at Harvard University and then returned to academia from 2006-2017 to serve as a Professor of the Practice in Molecular and Cell Biology at Harvard University and a Professor of Management Practice at Harvard Business School. Dr. Sato is currently on the Board of Directors at Denali Therapeutics, Vir Biotechnology and Akouos.

Owen Witte, M.D., is a University Professor of Microbiology, Immunology and Molecular Genetics, and Molecular and Medical Pharmacology at UCLA, where he holds the President’s Chair in Developmental Immunology at UCLA’s David Geffen School of Medicine. For 30 years, he was also an investigator with the Howard Hughes Medical Institute. Dr. Witte is also a member of the National Academy of Science and National Academy of Medicine. Dr. Witte currently serves on the Board of Directors of Allogene and previously served on the Board of Directors and the Scientific Advisory Board of Kite Pharma. He completed his postdoctoral research at the Massachusetts Institute of Technology Center for Cancer Research, working in the lab of Nobel Laureate Dr. David Baltimore. Dr. Witte also completed predoctoral research training in the lab of Dr. Irving Weissman while a medical student at Stanford University. He received his B.S. with highest honors in microbiology from Cornell University and his M.D. from Stanford University.